In this case it is important not to delay getting advice as your blood glucose levels can quickly rise to dangerous levels. Insulin glargine differs from human insulin in that the amino acid asparagine at position A21 is replaced by glycine and two arginines are added to the C terminus of the B chain. I may, at some point, find it necessary to supplement with my Metformin, but I would rather the LANTUS worked on its own to keep my BG “normal”, which to me means small spikes immediately after eating, etc. I use the Lantus SoloStar, which in my opinion is the best pen available for Lantus. Best Price* ₹ 578.03 MRP ₹722.54 (Inclusive of all taxes) * Get the best price on this product on orders above Rs 999. Insulin glargine is a long-acting insulin analogue with a flat and predictable action profile. Lantus Warnings You will be taught how to properly inject this medication since that is the only way to use it. What is Lantus? This quick reference guide is a short version of the instruction leaflet. Fundet i bogen – Side 183INJECTABLE INSULINS* physical activity, body temperature, and blood supply. ... When transferring from twice a day NPH human insulin, the initial Lantus dose should be reduced by about 20% from the previous total daily NPH dose, ... There does not appear to be a factual basis for maximum insulin glargine doses. Aside from this technical maximum, there is no mention of a maximum dose in the package insert. Insulin glargine comes as a solution (liquid) to inject subcutaneously (under the Please note: JavaScript is required to post comments. Contents of the pack and other information 1. If after reading and practicing insulin injections you still find you’re having trouble, Penney suggests seeing a Certified Diabetes Educator for more assistance. The concentration of insulin glargine in Toujeo® is 300 Units per mL. Lantus insulin is available in pre-filled devices, known as SoloSTAR Pens. The combination therapy is sold in a pen and features a three-to-one mixture of two different drugs, Sanofi’s basal insulin Lantus, and Sanofi/Zealand’s GLP-1 agonist Adlyxin (sold in Europe as Lyxumia). Lantus® (glargine insulin) – slow, steady release of insulin with no apparent peak action. Fundet i bogen – Side 1156Do not mix insulin detemir or insulin glargine with another insulin or solution. • Know that insulin degludec is now ... Inject insulin glargine once daily at any time, keeping the daily injection time consistent. Inject insulin detemir ... 1) Needles (30 gauge 1/2 inch needles) for injecting the insulin. Lantus is great, insulin is the most effective product you can use to treat diabetes and I would encourage you to continue Metformin as it has different mechanism of action including reducing the amount of glucose your liver makes. injection, equivalent to 1000 units. Fundet i bogen – Side 198INSULIN—INJECTABLE, LONG-ACTING (Lantus, acting insulin. UNAPPROVED ADULT — DM, Type 2 (ADA): When uncontrolled DM, start 4 units, 0.1 units/kg or 10% of basal dose with largest meal. Titrate up by 10 to 15% or 1 to 2 units once or ... In plasma, the principal circulating compound is … • Do not share needles, insulin pens, or syringes with others. ... Lantus® 40 units daily (80% of 50 units daily = 40 units) Information for Health Care Professionals Switching between Insulin Products in Disaster Response Situations Lantus is more popular than other insulins. It works like your body''s natural insulin. What’s the evidence? Cold insulin is more painful to inject. Because Max SoloStar gives you the most insulin units per pen, you may need to … Before starting Lantus®, tell your doctor about all your medical conditions, including if you have liver or kidney problems, if you are pregnant or planning to become pregnant or if you are breast-feeding or planning to breast-feed. A: Here are some easy guidelines: -Stomach If you’re going to inject into the stomach, stay at least two inches away from the bellybutton and/or any scars you may already have when using the abdomen for injections. Insulin glargine is a self-injectable solution used to control high blood sugar (hyperglycemia) in people with type 1 and type 2 diabetes. Do not allow it to freeze. LANTUS also contains zinc, metacresol, glycerol, and water for injection … Important Safety Information Lantus should NOT be used in infusion pumps as it could cause severe hypoglycemia. Mechanism of action. For example, inject your insulin above your belly button, then the next time use your upper thigh, then the next time below your belly button. Call your doctor for medical advice about side effects. What you need to know before you use Lantus 3. Protect SoloSTAR® from light. If you forgot to take your meal time injection more than 2 hours ago, it can be more complicated as you may have another meal or bed time due. Anecdotally, I have heard that patients receiving more than 50 units should split the dose from daily dosing to twice-daily. If you take insulin to manage your diabetes, you could be taking anywhere from 1 to 10 injections per day. Can you administer more than 50 units of insulin glargine as one single injection? Lantus (insulin glargine injection (rDNA origin)) is a recombinant human insulin analogue produced by DNA technology. We look at this common problem and provide some guidance. • Do not mix or dilute Lantus® with any other insulin or solution. Lantus (insulin glargine) is a recombinant human insulin analog with a duration of action up to 24 hours.1 The microprecipitates that are formed in the subcutaneous tissue after injection slow the absorption of Lantus and provide a relatively constant level of insulin over 24 hours without a pronounced peak.1 This prolonged effect over 24 hours enables it to be administered once daily. We guarantee your order will be shipped from a Licensed Canadian Pharmacy. You may need to read it again. Changes in insulin regimen may result in hyperglycemia or hypoglycemia. In some cases this could increase the chance of hypoglycaemia so speak to your health team if you have any doubts. Note: ClinCalc.com is intended for healthcare providers. You can clean the outside of your SoloSTAR® by wiping it with a damp cloth. Always remember that if you are at all unsure what to do, you should contact your health team for advice rather than risk making a mistake. Commonly cited reasons for missed injections include: If you have problems with forgetting injections, see our forgetting injections guide dedicated to help prevent problems with forgetting to inject and if you forget whether you have injected or not. Do not pass it on to others. This will help avoid medication errors such as mix ups with other medications. Always make sure you have the correct insulin before each injection. Rotate the location of the injection, and slightly change the injection spot each time you inject insulin. SoloSTAR® in use must not be stored in a refrigerator. Changing any of these factors can affect your blood sugar levels. It is usually injected once a day but can be taken twice daily. Why Lantus® (insulin glargine injection) 100 Units/mL May Be the Right Choice for You Improved blood sugar management. • Sterilize the top—Wipe the top of the vial with an alcohol swab. It has a long and steady (constant) effect on the blood sugar levels and the action lasts for an entire day. Lantus 100 units/ml solution for injection in a cartridge, Lantus SoloStar 100 units/ml solution for injection in a pre-filled pen Each cartridge or pen contains 3 ml of solution for injection, equivalent to 300 units. *Insulin glargine is produced by recombinant DNA technology in Escherichia coli. For the full list of excipients, see section 6.1. Can be a bit awkward to see exactly where I am injecting but is easy with a bit of practise. Insulin glargine is a recombinant human insulin analog that is a long-acting (up to 24-hour duration of action), parenteral blood-glucose-lowering agent [ See Clinical Pharmacology (12) ]. Lantus (insulin glargine) is a man-made injectable form of insulin used to regulate sugar (glucose) levels in type 1 and type 2 diabetes. Lantus 100IU/ml Solution for Injection 5 x 3 ml is for subcutaneous (under the skin) use only and should never be administered intravenously (IV) or in the veins. Allow the cat to finish eating undisturbed. Might be worth asking? An injectable drug, this medication works to regulate your diabetic cat's blood sugar. Lantus (insulin glargine injection (rDNA origin)) is a recombinant human insulin analogue produced by DNA technology. Find support, ask questions and share your experiences. Continue reading >>, Insulin glargine is used to treat type 1 diabetes (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood). Toujeo contains the same active ingredient, insulin glargine, as Lantus ®. This book presents the author's knowledge and expertise acquired after a full year of a diabetes fellowship, and it is inspired by the author's own experiences managing diabetes before and after the fellowship, containing the discoveries ... Penney sat down with us recently to answer some common questions about insulin injection. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes. 2006;23(8):879-86. Insulin pens and needles must never be shared between patients. Insulin glargine, the variant of insulin in Lantus, is a long-acting form of insulin that begins to work several hours after the injection is administered. Learn more. LANTUS is produced by recombinant DNA technology utilizing a non-pathogenic laboratory strain of Escherichia coli (K12) as the production organism. If you forget to take your long term insulin (basal insulin) and you realise relatively soon, it should usually be fine to inject your usual dose if the dose is given within 2 hours of when it should have been done. The headline you’ve probably read more than once, including here on A Sweet Life, is one of outrage surrounding rumors... Here’s a sticking point for diabetics: the cost of insulin more than tripled — from $231 to $736 a year per patient ... 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Continue reading >>, Package leaflet: Information for the user Lantus® SoloStar® 100 units/ml solution for injection in a pre-filled pen Read all of this leaflet carefully including the Instructions for Use of Lantus SoloStar, pre- filled pen, before you start using this medicine because it contains important information for you. Any change in this medicine should be made cautiously and only under medical supervision. The upper outer area of the arms. Fundet i bogen – Side 30(insulin. glargine. [rDNA. origin]. injection). LANTUS* must NOT be diluted or mixed with any other insulin or solution. INDICATIONS AND USAGE LANTUS is indicated for once-daily subcutaneous administration for the treatment of adult and ... Hypoglycemia is the most common side effect with insulin therapy and may be life-threatening. "With proper practice and good technique, you can avoid pain during an injection," she states. At pH 4, as in the LANTUS injection solution, insulin glargine is completely soluble. Find support, ask questions and share your experiences with 328,007 members of the diabetes community. You can also go online to Lantus.com or call the support line at 1-800-633-1610. Do NOT reuse needles. Reading this guide will help to make sure that you inject the right amount of insulin every time. Insulin glargine is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Lantus 100 IU/mL solution for injection in 3 mL cartridges.
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